Projects

BRANDY: Brain Network Dynamics

Methods

  • coordination of common teaching activities
  • support of students’ interest and engagement in brain network dynamics throughout all stages of their early academic carrier
  • formation of a collaborative environment for young academics

Objectives

  • Foundation of a Strategic Unit for the Interdisciplinary Research on Brain Network Dynamics
  • Creation of a cluster of experts in this fast growing field of research
  • Development of an infrastructure, optimized for information exchange among the partners
  • Formation of a collaborative environment for young academics with different skills for common research initiatives
  • Generation of visibility of our actions for the international research community

Project coordinator

  • Albrecht Haase (DF & CIMeC)

Partners

Center for Mind/Brain Sciences (CIMeC)

  Department of Physics (DF)

Department of Information Engineering and Computer Sciences (DISI)

Centre for Integrative Biology (CIBIO)

Fondazione Bruno Kessler (FBK)

Italian Institute of Technology (IIT)

Financing

Sublethal effects of neonicotinoids on the honeybee brain: from single neuron imaging to colony studies.

Methods

  • functional imaging of different regions along the odour processing pathway
  • controlled perfusion of the brain with active substances during imaging
  • comparative behavioural studies unsing PER

Objectives

  • determine brain regions sensitive to neonicotinoid pesticides
  • quantify relevant doses for onset of effects in the olfactory system
  • compare effects in the brain to behavioural symtoms in field studies

Project coordinator

  • Albrecht Haase (DF & CIMeC)

Partners

Financing

  • 3 year project financed by the Provincia autonoma di Bolzano

Of bees and men: Development of an optogenetic animal model to study oscillatory neural networks.

Methods

  • high temporal resolution imaging of respones to odour stimuli
  • analysis of oscillatory activity in the honeybee brain
  • development of an optogenetic toolbox for real-time modulation of the olfactory processing network

Objectives

  • temporal coding in odour perception
  • connectivity in the olfactory network
  • changes in the network properties under optogenetic modulation of single nodes

Project coordinator

  • Albrecht Haase (DF & CIMeC)

Partners

Financing

  • as a Strategic Project by the Università degli studi di Trento

Fundamental processes in odorant receptor interaction: beyond the shape theory of olfaction

Methods

  • studying odour coding of compounds that share chemical properties but differ in molecular vibration and vice versa
  • develope in vitro essays to study odour receptor interaction

Objectives

  • trace back insects' ability to destiguish chemically identical odour compounds
  • study possible influence of molecular vibrations
  • exclude alternative explainations for differential odour coding

Partners

Financing

  • supported by an EMBO Short-Term Fellowship ASTF 108-2015

Insect brain imaging: from fundamental neuroscience to pest control

Methods

  • two-photon in vivo imaging of insect brains in vivo to outperform conventional microscopy by spatial and temporal resolution, penetration depth and photodamage limitation

Objectives

  • Odour coding principles in the honeybee brain
  • Morphological and functional plasticity in the honeybee brain after associative or non-associative learning
  • In of odour perception due to neurotoxic pesticides as a possible cause for the western world honeybee population decline (Colony Collapse Disorder)

Project coordinator

  • Albrecht Haase (DF & CIMeC)

Financing

  •  as Research unit (IBRAIM) by the Provincia Autonoma di Trento

Sustainable strategies against infesting flies: from olfactory perception to a safeguard of small fruits in Trentino

Methods

  • behaviour experiments in Drosophila melanogaster and Drosophila suzukii
  • optical imaging of transgenetic fruitflies

Objectives

  • differences between D. suzukii e D. melanogaster regarding reception, behaviour, and neuroanatomy.
  • development of sostainable strategies to explore these results to couteract the diffusion of D. suzukii.

Project coordinator

  • Albrecht Haase (DF & CIMeC)

Partners

Financing

  • by the Communal Government of the City of Rovereto

Multifunctional nanohybrid photosensitizers for Photodynamic therapy via X-ray and IR activation

Methods

  • synthetization and functionalization of photo-sensitive silicon Nanowires
  • in vitro experiments on IR activation, and quantification of phototoxic effects

Objectives

  • development of a photosensitizer that is fexibly activatible at very different wavelength
  • characterization of functionality in cell cultures

Project coordinator

Partners

  • Roberta Tatti (IMEM, CNR)
  • Albrecht Haase and Renzo Antolini (DF and CIMeC)
  • Thomas Paternoster and Nicola Berti (Sandoz Industries)

Financing

  •  by Fondazione Cassa di risparmio di Trento e Rovereto